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Gene Function Associations in Species Genomes

Deviations in gene matches for GO categories by species genomes.

These deviations suggest where species may differ in biological function groups.
Target species genomes: Dro.mel, Dro.sim, Dro.sec, Dro.yak, Dro.ere, Dro.ana, Dro.per, Dro.pse, Dro.wil, Dro.moj, Dro.vir, Dro.gri
Source proteome: Mouse [version 9g3]
Click on term for detailed information, or see here.
GO ID  
dmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
Term & Grouping
GO:0003743 translation initiation factor activity F : binding
GO:0005041 low-density lipoprotein receptor activity F : binding
GO:0005178 integrin binding F : binding
GO:0005179 hormone activity F : binding
GO:0005515 protein binding F : binding
GO:0005529 sugar binding F : binding
GO:0005537 mannose binding F : binding
GO:0005544 calcium-dependent phospholipid binding F : binding
GO:0008143 poly(A) binding F : binding
GO:0019838 growth factor binding F : binding
GO:0030151 molybdenum ion binding F : binding
GO:0050661 NADP binding F : binding
GO:0004016 adenylate cyclase activity F : catalytic activity
GO:0004031 aldehyde oxidase activity F : catalytic activity
GO:0004104 cholinesterase activity F : catalytic activity
GO:0004175 endopeptidase activity F : catalytic activity
GO:0004179 membrane alanyl aminopeptidase activity F : catalytic activity
GO:0004180 carboxypeptidase activity F : catalytic activity
GO:0004182 carboxypeptidase A activity F : catalytic activity
GO:0004190 aspartic-type endopeptidase activity F : catalytic activity
GO:0004222 metalloendopeptidase activity F : catalytic activity
GO:0004245 neprilysin activity F : catalytic activity
GO:0004252 serine-type endopeptidase activity F : catalytic activity
GO:0004263 chymotrypsin activity F : catalytic activity
GO:0004295 trypsin activity F : catalytic activity
GO:0004298 threonine endopeptidase activity F : catalytic activity
GO:0004559 alpha-mannosidase activity F : catalytic activity
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity F : catalytic activity
GO:0004840 ubiquitin conjugating enzyme activity F : catalytic activity
GO:0004842 ubiquitin-protein ligase activity F : catalytic activity
GO:0008132 pancreatic elastase activity F : catalytic activity
GO:0008233 peptidase activity F : catalytic activity
GO:0008236 serine-type peptidase activity F : catalytic activity
GO:0008237 metallopeptidase activity F : catalytic activity
GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity F : catalytic activity
GO:0015923 mannosidase activity F : catalytic activity
GO:0016491 oxidoreductase activity F : catalytic activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor F : catalytic activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen F : catalytic activity
GO:0016757 transferase activity, transferring glycosyl groups F : catalytic activity
GO:0016789 carboxylic ester hydrolase activity F : catalytic activity
GO:0018685 alkane 1-monooxygenase activity F : catalytic activity
GO:0035250 UDP-galactosyltransferase activity F : catalytic activity
GO:0050381 unspecific monooxygenase activity F : catalytic activity
GO:0005085 guanyl-nucleotide exchange factor activity F : enzyme regulator activity
GO:0030414 protease inhibitor activity F : enzyme regulator activity
GO:0045735 nutrient reservoir activity F : nutrient reservoir activity
GO:0001584 rhodopsin-like receptor activity F : signal transducer activity
GO:0004871 signal transducer activity F : signal transducer activity
GO:0004872 receptor activity F : signal transducer activity
GO:0004890 GABA-A receptor activity F : signal transducer activity
GO:0004930 G-protein coupled receptor activity F : signal transducer activity
GO:0004935 adrenoceptor activity F : signal transducer activity
GO:0004936 alpha-adrenergic receptor activity F : signal transducer activity
GO:0004952 dopamine receptor activity F : signal transducer activity
GO:0004984 olfactory receptor activity F : signal transducer activity
GO:0004993 serotonin receptor activity F : signal transducer activity
GO:0004995 tachykinin receptor activity F : signal transducer activity
GO:0005044 scavenger receptor activity F : signal transducer activity
GO:0017154 semaphorin receptor activity F : signal transducer activity
GO:0030594 neurotransmitter receptor activity F : signal transducer activity
GO:0030020 extracellular matrix structural constituent conferring tensile strength F : structural molecule activity
GO:0016563 transcriptional activator activity F : transcription regulator activity
GO:0005230 extracellular ligand-gated ion channel activity F : transporter activity
GO:0005245 voltage-gated calcium channel activity F : transporter activity
GO:0005262 calcium channel activity F : transporter activity
GO:0005302 L-tyrosine transporter activity F : transporter activity
GO:0005319 lipid transporter activity F : transporter activity
GO:0005391 sodium:potassium-exchanging ATPase activity F : transporter activity
GO:0008273 calcium, potassium:sodium antiporter activity F : transporter activity
GO:0015077 monovalent inorganic cation transporter activity F : transporter activity
GO:0015114 phosphate transporter activity F : transporter activity
GO:0015180 L-alanine transporter activity F : transporter activity
GO:0015193 L-proline transporter activity F : transporter activity
GO:0016934 glycine-gated chloride channel activity F : transporter activity
GO ID  
dmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
Term & Grouping
GO:0001504 neurotransmitter uptake P : cellular process
GO:0007160 cell-matrix adhesion P : cellular process
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway P : cellular process
GO:0007186 G-protein coupled receptor protein signaling pathway P : cellular process
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger P : cellular process
GO:0007229 integrin-mediated signaling pathway P : cellular process
GO:0007266 Rho protein signal transduction P : cellular process
GO:0007268 synaptic transmission P : cellular process
GO:0016337 cell-cell adhesion P : cellular process
GO:0016601 Rac protein signal transduction P : cellular process
GO:0030154 cell differentiation P : cellular process
GO:0001503 ossification P : development
GO:0001525 angiogenesis P : development
GO:0045766 positive regulation of angiogenesis P : development
GO:0000059 protein import into nucleus, docking P : physiological process
GO:0000103 sulfate assimilation P : physiological process
GO:0001539 ciliary or flagellar motility P : physiological process
GO:0005977 glycogen metabolism P : physiological process
GO:0006013 mannose metabolism P : physiological process
GO:0006171 cAMP biosynthesis P : physiological process
GO:0006334 nucleosome assembly P : physiological process
GO:0006397 mRNA processing P : physiological process
GO:0006471 protein amino acid ADP-ribosylation P : physiological process
GO:0006508 proteolysis P : physiological process
GO:0006512 ubiquitin cycle P : physiological process
GO:0006695 cholesterol biosynthesis P : physiological process
GO:0006812 cation transport P : physiological process
GO:0006814 sodium ion transport P : physiological process
GO:0006817 phosphate transport P : physiological process
GO:0006874 calcium ion homeostasis P : physiological process
GO:0006956 complement activation P : physiological process
GO:0006958 complement activation, classical pathway P : physiological process
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota) P : physiological process
GO:0007009 plasma membrane organization and biogenesis P : physiological process
GO:0007411 axon guidance P : physiological process
GO:0007601 visual perception P : physiological process
GO:0009312 oligosaccharide biosynthesis P : physiological process
GO:0015672 monovalent inorganic cation transport P : physiological process
GO:0015711 organic anion transport P : physiological process
GO:0015800 acidic amino acid transport P : physiological process
GO:0015808 L-alanine transport P : physiological process
GO:0015824 proline transport P : physiological process
GO:0015991 ATP hydrolysis coupled proton transport P : physiological process
GO:0016926 protein desumoylation P : physiological process
GO:0019835 cytolysis P : physiological process
GO:0030574 collagen catabolism P : physiological process
GO:0042744 hydrogen peroxide catabolism P : physiological process
GO:0050885 regulation of balance P : physiological process
GO:0050974 detection of mechanical stimulus during sensory perception P : physiological process
GO:0051325 interphase P : physiological process
GO:0016481 negative regulation of transcription P : regulation of biological process
GO:0042108 positive regulation of cytokine biosynthesis P : regulation of biological process
GO:0045595 regulation of cell differentiation P : regulation of biological process
GO:0045941 positive regulation of transcription P : regulation of biological process
GO:0046324 regulation of glucose import P : regulation of biological process
GO:0006935 chemotaxis P : response to stimulus
GO:0006953 acute-phase response P : response to stimulus
GO:0007602 phototransduction P : response to stimulus
GO:0007611 learning and/or memory P : response to stimulus
GO:0007613 memory P : response to stimulus
GO:0008344 adult locomotory behavior P : response to stimulus
GO:0009605 response to external stimulus P : response to stimulus
GO:0042221 response to chemical stimulus P : response to stimulus
GO ID  
dmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
Term & Grouping
GO:0000139 Golgi membrane C : cell part
GO:0005911 intercellular junction C : cell part
GO:0009986 cell surface C : cell part
GO:0019866 organelle inner membrane C : cell part
GO:0030027 lamellipodium C : cell part
GO:0030054 cell junction C : cell part
GO:0030425 dendrite C : cell part
GO:0030672 synaptic vesicle membrane C : cell part
GO:0005635 nuclear envelope C : envelope
GO:0005581 collagen C : extracellular matrix part
GO:0005578 extracellular matrix (sensu Metazoa) C : extracellular matrix
GO:0005615 extracellular space C : extracellular region part
GO:0044421 extracellular region part C : extracellular region part
GO:0005576 extracellular region C : extracellular region
GO:0000775 chromosome, pericentric region C : organelle part
GO:0005882 intermediate filament C : organelle part
GO:0001533 cornified envelope C : organelle
GO:0005694 chromosome C : organelle
GO:0000786 nucleosome C : protein complex
GO:0005643 nuclear pore C : protein complex
GO:0005667 transcription factor complex C : protein complex
GO:0005839 proteasome core complex (sensu Eukaryota) C : protein complex
GO:0005891 voltage-gated calcium channel complex C : protein complex
 
dmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri

Find crosstable statistics here.

No significant deviations for n= 943 categories.

Developed at the Genome Informatics Lab of Indiana University Biology Department