| |||||||||
Index of /species/news/genome-summaries/gene-GO-function-association/genes6-cele5-mouse-v9g3
Deviations in gene matches for GO categories by species genomes.These deviations suggest where species may differ in biological function groups.Target species genomes: C.elegans, Daphnia_pulex, Dro.mel, Dro.pse, Dro.vir Source proteome: Mouse [version 9g3] Gene Function Associations in Species Genomes Deviations in gene matches for GO categories by species genomes. Summary of table: genes6-cele5-mouse-v9g3/index-summary-crosstab.txt Minimum Chi^2 per row: 5 goterm cele dpul dmel dpse dvir Ng Term and Grouping GO:0004601 + +++ - - - 33 peroxidase activity, F:antioxidant activity GO:0004602 +++ +++ - -- -- 5 glutathione peroxidase activity, F:antioxidant activity GO:0003676 - ---- +++ . ++ 471 nucleic acid binding, F:binding GO:0005041 ++ --- . . + 4 low-density lipoprotein receptor activity, F:binding GO:0005496 +++++ - - - . 26 steroid binding, F:binding GO:0005529 ++++ -- -- + - 74 sugar binding, F:binding GO:0009374 . ++++ - - - 4 biotin binding, F:binding GO:0019001 ++++ - . - -- 17 guanyl nucleotide binding, F:binding GO:0030151 . --- . +++ . 8 molybdenum ion binding, F:binding GO:0046872 --- - ++ . + 1207 metal ion binding, F:binding GO:0050897 . +++ . - - 7 cobalt ion binding, F:binding GO:0003796 --- --- + ++ ++ 5 lysozyme activity, F:catalytic activity GO:0003810 -- +++++ - - - 3 protein-glutamine gamma-glutamyltransferase activity, F:catalytic activity GO:0004016 --- ---- ++++ ++ . 15 adenylate cyclase activity, F:catalytic activity GO:0004062 -- ++++ - - . 4 aryl sulfotransferase activity, F:catalytic activity GO:0004089 --- +++++ -- . . 25 carbonate dehydratase activity, F:catalytic activity GO:0004175 . --- . ++ + 34 endopeptidase activity, F:catalytic activity GO:0004178 --- . . + + 10 leucyl aminopeptidase activity, F:catalytic activity GO:0004179 ---- ++ . . + 26 membrane alanyl aminopeptidase activity, F:catalytic activity GO:0004190 ++++ -- . . -- 13 aspartic-type endopeptidase activity, F:catalytic activity GO:0004194 +++++ -- . . -- 13 pepsin A activity, F:catalytic activity GO:0004239 -- +++ - . . 8 methionyl aminopeptidase activity, F:catalytic activity GO:0004245 ++ ---- - ++ + 8 neprilysin activity, F:catalytic activity GO:0004252 ----- +++++ + . . 140 serine-type endopeptidase activity, F:catalytic activity GO:0004263 ----- ++ ++ + . 41 chymotrypsin activity, F:catalytic activity GO:0004293 --- ++ + . . 7 tissue kallikrein activity, F:catalytic activity GO:0004295 ----- +++ + + . 41 trypsin activity, F:catalytic activity GO:0004383 ++ --- . . . 19 guanylate cyclase activity, F:catalytic activity GO:0004435 . +++ - - . 5 phosphoinositide phospholipase C activity, F:catalytic activity GO:0004568 ---- +++ . . . 12 chitinase activity, F:catalytic activity GO:0004629 . +++ - - . 6 phospholipase C activity, F:catalytic activity GO:0004713 . +++ - - . 163 protein-tyrosine kinase activity, F:catalytic activity GO:0004714 - +++++ - -- - 24 transmembrane receptor protein tyrosine kinase activity, F:catalytic activity GO:0004721 + --- . + . 76 phosphoprotein phosphatase activity, F:catalytic activity GO:0004840 . -- - +++ . 24 ubiquitin conjugating enzyme activity, F:catalytic activity GO:0004842 - --- . +++ + 66 ubiquitin-protein ligase activity, F:catalytic activity GO:0005021 - +++++ . -- . 7 vascular endothelial growth factor receptor activity, F:catalytic activity GO:0008132 --- +++ --- . + 5 pancreatic elastase activity, F:catalytic activity GO:0008146 --- +++++ - . . 25 sulfotransferase activity, F:catalytic activity GO:0008233 ----- +++ . ++ + 407 peptidase activity, F:catalytic activity GO:0008237 --- ++ -- + + 149 metallopeptidase activity, F:catalytic activity GO:0008378 -- +++++ - . . 24 galactosyltransferase activity, F:catalytic activity GO:0008395 +++ - - . . 6 steroid hydroxylase activity, F:catalytic activity GO:0008417 . +++++ -- - -- 12 fucosyltransferase activity, F:catalytic activity GO:0008499 . +++ - . - 10 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, F:catalytic activity GO:0008745 -- --- . +++ ++ 4 N-acetylmuramoyl-L-alanine amidase activity, F:catalytic activity GO:0016491 . +++ . -- -- 504 oxidoreductase activity, F:catalytic activity GO:0016712 +++++ - . -- - 35 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, F:catalytic activity GO:0016740 ++ ++++ - -- -- 863 transferase activity, F:catalytic activity GO:0016787 ----- ++ . + + 982 hydrolase activity, F:catalytic activity GO:0016798 ---- + ++ . . 53 hydrolase activity, acting on glycosyl bonds, F:catalytic activity GO:0016849 . ---- +++ ++ . 28 phosphorus-oxygen lyase activity, F:catalytic activity GO:0050381 +++ . . - - 33 unspecific monooxygenase activity, F:catalytic activity GO:0004867 . --- ++ + . 57 serine-type endopeptidase inhibitor activity, F:enzyme regulator activity GO:0001584 + + --- + - 102 rhodopsin-like receptor activity, F:signal transducer activity GO:0003707 +++++ - - - -- 29 steroid hormone receptor activity, F:signal transducer activity GO:0004879 +++++ - - - - 28 ligand-dependent nuclear receptor activity, F:signal transducer activity GO:0004890 ++++ + -- -- - 31 GABA-A receptor activity, F:signal transducer activity GO:0004926 -- -- . +++ + 6 non-G-protein coupled 7TM receptor activity, F:signal transducer activity GO:0004935 + - --- ++ + 14 adrenoceptor activity, F:signal transducer activity GO:0005070 - - +++ . . 7 SH3/SH2 adaptor activity, F:signal transducer activity GO:0008158 +++++ . . -- - 5 hedgehog receptor activity, F:signal transducer activity GO:0016019 -- --- . +++ ++ 4 peptidoglycan receptor activity, F:signal transducer activity GO:0017154 . -- ++++ -- . 3 semaphorin receptor activity, F:signal transducer activity GO:0030594 ++++ + - --- - 39 neurotransmitter receptor activity, F:signal transducer activity GO:0045028 ++++ . - -- . 9 purinergic nucleotide receptor activity, G-protein coupled, F:signal transducer activity GO:0005198 ++++ . -- . - 159 structural molecule activity, F:structural molecule activity GO:0005201 +++++ -- -- - -- 38 extracellular matrix structural constituent, F:structural molecule activity GO:0030020 +++++ + ---- -- ---- 38 extracellular matrix structural constituent conferring tensile strength, F:structural molecule activity GO:0004889 + +++ - -- - 21 nicotinic acetylcholine-activated cation-selective channel activity, F:transporter activity GO:0005215 ---- - + ++ ++ 299 transporter activity, F:transporter activity GO:0005216 ++++ . . -- - 170 ion channel activity, F:transporter activity GO:0005230 +++++ + - --- - 42 extracellular ligand-gated ion channel activity, F:transporter activity GO:0005249 +++ -- + . - 40 voltage-gated potassium channel activity, F:transporter activity GO:0005254 - +++++ - -- - 3 chloride channel activity, F:transporter activity GO:0005272 +++++ --- - + - 7 sodium channel activity, F:transporter activity GO:0005338 ++++ . - -- - 3 nucleotide-sugar transporter activity, F:transporter activity GO:0008559 +++ -- . . . 7 xenobiotic-transporting ATPase activity, F:transporter activity GO:0015075 --- -- + + ++ 29 ion transporter activity, F:transporter activity GO:0015114 +++++ . - -- -- 7 phosphate transporter activity, F:transporter activity GO:0015280 +++++ --- -- + - 7 amiloride-sensitive sodium channel activity, F:transporter activity GO:0015293 --- ++ . + - 101 symporter activity, F:transporter activity GO:0015299 ++ +++ -- -- . 6 solute:hydrogen antiporter activity, F:transporter activity GO:0015377 - +++++ - - -- 10 cation:chloride symporter activity, F:transporter activity Over/Under +31/-27 +34/-26 +9/-13 +14/-19 +6/-12 Relative amount of over- and under-representation in groups (not gene counts) goterm cele dpul dmel dpse dvir Ng Term and Grouping GO:0007155 +++ - - . . 234 cell adhesion, P:cellular process GO:0007169 . ++++ . -- - 30 transmembrane receptor protein tyrosine kinase signaling pathway, P:cellular process GO:0007214 +++++ . - --- . 8 gamma-aminobutyric acid signaling pathway, P:cellular process GO:0007286 --- - ++ . ++ 11 spermatid development, P:cellular process GO:0030154 -- . . . +++ 192 cell differentiation, P:cellular process GO:0030518 +++++ - - - . 4 steroid hormone receptor signaling pathway, P:cellular process GO:0001502 +++++ . -- - . 8 cartilage condensation, P:development GO:0000103 -- +++++ - -- . 5 sulfate assimilation, P:physiological process GO:0000270 -- ++++ - - . 6 peptidoglycan metabolism, P:physiological process GO:0001516 ++++ + - -- -- 8 prostaglandin biosynthesis, P:physiological process GO:0001539 - -- . . +++ 5 ciliary or flagellar motility, P:physiological process GO:0005977 + --- . + . 21 glycogen metabolism, P:physiological process GO:0006029 +++ . -- . . 10 proteoglycan metabolism, P:physiological process GO:0006032 ---- +++ . . . 12 chitin catabolism, P:physiological process GO:0006171 --- ---- ++++ ++ . 15 cAMP biosynthesis, P:physiological process GO:0006182 ++++ -- . . . 15 cGMP biosynthesis, P:physiological process GO:0006486 . +++++ -- - --- 26 protein amino acid glycosylation, P:physiological process GO:0006508 ----- ++++ . + . 392 proteolysis, P:physiological process GO:0006511 -- --- . +++ + 76 ubiquitin-dependent protein catabolism, P:physiological process GO:0006631 +++ . . -- . 55 fatty acid metabolism, P:physiological process GO:0006730 --- +++++ - . - 38 one-carbon compound metabolism, P:physiological process GO:0006783 --- ++ . . . 9 heme biosynthesis, P:physiological process GO:0006817 +++++ ++ ---- --- ----- 49 phosphate transport, P:physiological process GO:0006821 +++ +++++ --- ---- -- 40 chloride transport, P:physiological process GO:0006897 +++++ -- - - . 72 endocytosis, P:physiological process GO:0006979 ++ +++ - -- - 32 response to oxidative stress, P:physiological process GO:0007010 +++ - . - . 57 cytoskeleton organization and biogenesis, P:physiological process GO:0007586 -- +++ - + . 14 digestion, P:physiological process GO:0009190 . ---- +++ ++ . 28 cyclic nucleotide biosynthesis, P:physiological process GO:0009253 -- --- . +++ ++ 4 peptidoglycan catabolism, P:physiological process GO:0009312 . +++ -- . - 9 oligosaccharide biosynthesis, P:physiological process GO:0015695 --- - + + + 5 organic cation transport, P:physiological process GO:0015780 ++++ . - -- - 3 nucleotide-sugar transport, P:physiological process GO:0018149 -- +++++ - - - 3 peptide cross-linking, P:physiological process GO:0018298 -- ++++ -- . - 10 protein-chromophore linkage, P:physiological process GO:0019395 +++ . . . - 5 fatty acid oxidation, P:physiological process GO:0030198 + +++ - - - 13 extracellular matrix organization and biogenesis, P:physiological process GO:0030199 +++++ - -- - . 5 collagen fibril organization, P:physiological process GO:0030574 -- ++++ . - . 8 collagen catabolism, P:physiological process GO:0042744 . ++++ -- -- . 10 hydrogen peroxide catabolism, P:physiological process GO:0046777 +++ . . -- - 10 protein amino acid autophosphorylation, P:physiological process GO:0050974 . -- - +++ . 6 detection of mechanical stimulus during sensory perception, P:physiological process GO:0051260 . +++ -- - - 7 protein homooligomerization, P:physiological process GO:0051325 +++ . . . -- 10 interphase, P:physiological process GO:0048066 - . +++ . - 11 pigmentation during development, P:pigmentation GO:0007190 -- ---- +++ +++ . 16 adenylate cyclase activation, P:regulation of biological process GO:0009968 --- ++ . . . 21 negative regulation of signal transduction, P:regulation of biological process GO:0045665 --- - + ++ + 12 negative regulation of neuron differentiation, P:regulation of biological process GO:0045944 +++ . - -- . 73 positive regulation of transcription from RNA polymerase II promoter, P:regulation of biological process GO:0046324 . +++ -- . . 4 regulation of glucose import, P:regulation of biological process GO:0006954 -- ++++ - . . 31 inflammatory response, P:response to stimulus GO:0042742 -- --- ++ ++ ++ 8 defense response to bacterium, P:response to stimulus Over/Under +19/-21 +22/-11 +6/-11 +8/-12 +5/-5 Relative amount of over- and under-representation in groups (not gene counts) goterm cele dpul dmel dpse dvir Ng Term and Grouping GO:0005624 +++ . - . . 157 membrane fraction, C:cell part GO:0005792 ++++ --- . - . 129 microsome, C:cell part GO:0005929 ---- -- + ++ ++ 20 cilium, C:cell part GO:0019867 -- --- + +++ . 34 outer membrane, C:cell part GO:0030425 - --- +++ . . 14 dendrite, C:cell part GO:0046581 ++ ---- . . . 15 intercellular canaliculus, C:cell part GO:0005581 +++++ ++ ---- -- ---- 40 collagen, C:extracellular matrix part GO:0005578 +++++ + ---- -- - 126 extracellular matrix (sensu Metazoa), C:extracellular matrix GO:0005634 -- --- +++ . ++ 1783 nucleus, C:organelle GO:0005694 ++ + . --- . 67 chromosome, C:organelle GO:0005783 +++ -- . . . 387 endoplasmic reticulum, C:organelle GO:0005794 ++++ . . -- - 88 Golgi apparatus, C:organelle GO:0016023 --- + . . + 43 cytoplasmic membrane-bound vesicle, C:organelle GO:0000786 . + + ----- + 29 nucleosome, C:protein complex GO:0005858 -- -- . . +++ 11 axonemal dynein complex, C:protein complex GO:0008076 ++++ - . . -- 26 voltage-gated potassium channel complex, C:protein complex GO:0016459 ++ --- . . . 28 myosin complex, C:protein complex GO:0030286 -- ---- + ++ ++ 25 dynein complex, C:protein complex GO:0030529 . --- ++ . . 194 ribonucleoprotein complex, C:protein complex GO:0045202 - --- ++ . + 45 synapse, C:synapse Over/Under +10/-6 +1/-12 +4/-2 +3/-5 +4/-2 Relative amount of over- and under-representation in groups (not gene counts) |