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Number of gene matches (HSP groups) to Gene Ontology classes
in Drosophila species genomes
GO_Function category, Mouse,Worm,Yeast proteome

Legend: Blue bars: Mean gene count +/- 90% confidence interval
Red circle: expected value (population mean)

DNA binding RNA binding actin binding antioxidant activity binding
calcium ion binding carbohydrate binding catalytic activity chaperone regulator activity chromatin binding
cytoskeletal protein binding electron transporter activity enzyme regulator activity hydrolase activity ion channel activity
kinase activity lipid binding molecular_function unknown motor activity neurotransmitter transporter activity
nuclease activity nucleic acid binding nucleotide binding nutrient reservoir activity peptidase activity
phosphoprotein phosphatase activity protein binding protein kinase activity receptor activity receptor binding
signal transducer activity structural molecule activity transcription factor activity transcription regulator activity transferase activity
translation factor activity, nucleic acid binding translation regulator activity transporter activity

GO:0000166 nucleotide binding


GO:0000166 Significant 11 of 1841 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:104896122222222222
MGI:1330294112222222223
WBGene00011039112221222222
WBGene00004389112222122222
MGI:1914903112222222332
WBGene00000188111222332322
WBGene00020668112322222332
WBGene00000771111212222212
WBGene00011992222322222213
MGI:2444973112322332222
MGI:95527113221113313

GO:0003676 nucleic acid binding


GO:0003676 Significant 11 of 344 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:99185122321231111
WBGene00010325111211112111
MGI:1858435111211121211
WBGene00003231121331231111
MGI:1341890122411111111
WBGene00000466131222122111
MGI:1914289111221121121
MGI:1924367123322232231
MGI:107628212322442111
WBGene00022738122211322211
MGI:104688111112232121

GO:0003677 DNA binding


GO:0003677 Significant 11 of 1089 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:1935147423132211211
WBGene00017535322232322222
WBGene00012000323332222222
MGI:102688213231111112
WBGene00017847211132112112
MGI:1927549222222112122
WBGene00000428333331111122
MGI:96186222222111222
MGI:102778323333222333
WBGene00001971334323112212
WBGene00001972311113112111

GO:0003682 chromatin binding

No significant difference from population mean. See means plot

GO:0003700 transcription factor activity

No significant difference from population mean. See means plot

GO:0003723 RNA binding

No significant difference from population mean. See means plot

GO:0003774 motor activity


GO:0003774 Significant 11 of 38 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:107736446564574656
S00000471544118913986669
S000006174114322115212
S0000007874595768135557
MGI:1922715558786554655
S0000000275258576312856
S00000161264871098611595
S000006076557454654122
S0000058536621121215101113101511
S000001065437911412131216613
S000003074223222452323

GO:0003779 actin binding

No significant difference from population mean. See means plot

GO:0003824 catalytic activity


GO:0003824 Significant 11 of 2461 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:891990222222223222
WBGene00003066222222223222
WBGene00009903222222223222
MGI:98917212222223111
WBGene00016266112223223222
WBGene00022056122222213221
MGI:106040112223313111
MGI:95420112222124121
S000004622222323224122
WBGene00009738211222323121
S000001219212222214222

GO:0004518 nuclease activity


GO:0004518 Significant 11 of 101 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
S000005440111111111121
S000001300111121111111
S000004097111222212111
S000000432111211111111
WBGene00003828111211111111
S000005502111211112111
S000002688111111113121
S000007263001111211111
S000007271000013014241
WBGene00019535000111010000
WBGene00019264101111110000

GO:0004672 protein kinase activity

No significant difference from population mean. See means plot

GO:0004721 phosphoprotein phosphatase activity

No significant difference from population mean. See means plot

GO:0004871 signal transducer activity

No significant difference from population mean. See means plot

GO:0004872 receptor activity


GO:0004872 Significant 11 of 3715 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:109148111111011111
MGI:1335096111111011111
MGI:1860079111111011111
MGI:1918361111111011111
MGI:1934134111111011111
MGI:2177477111111011111
MGI:2177490111111011111
MGI:2177506111111011111
MGI:2177507111111011111
MGI:3030020111111011111
MGI:3030081111111011111

GO:0005102 receptor binding


GO:0005102 Significant 11 of 357 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:101875000000000110
WBGene00020722000000000101
MGI:1933833000000000111
MGI:2442071231111112211
MGI:3045960222454532642
MGI:1860236123222232311
WBGene00018925212212331323
MGI:107557222221112211
MGI:1919963243132654563
MGI:1890473000000300295140
WBGene00000936335445555665

GO:0005198 structural molecule activity


GO:0005198 Significant 11 of 1012 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:1928139111111221111
S000003068111111221111
S000003446111111221111
MGI:98105111111222111
S000002233111111222111
S000004398111111222111
MGI:1913659111111121111
MGI:1913743111111121111
S000001063111111121111
S000003380111111121111
WBGene00000724111111121111

GO:0005215 transporter activity


GO:0005215 Significant 11 of 1141 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
S000000308111113213322
WBGene00008123111222222222
S000006165112112222223
WBGene00009499112211222332
MGI:2653235122222224322
S000001840111112122332
S000003159222222223332
MGI:2384871113214224233
S000001138111222114222
WBGene00009618112212211222
MGI:1350931222223213423

GO:0005216 ion channel activity

No significant difference from population mean. See means plot

GO:0005326 neurotransmitter transporter activity

No significant difference from population mean. See means plot

GO:0005488 binding


GO:0005488 Significant 11 of 3373 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:103251111222222122
MGI:101932121212122112
MGI:1858493111211222112
MGI:2442117112222222122
MGI:107187111221222111
MGI:108495111112222111
MGI:88017111112222111
MGI:2144529112222222221
WBGene00003901111212321111
MGI:107622111122222111
WBGene00000158111211222121

GO:0005489 electron transporter activity


GO:0005489 Significant 11 of 63 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:106558111111113211
S000000765111111112111
S000001305111111112111
WBGene00022380111111112111
MGI:1914325121111111121
WBGene000109670120129277101
WBGene00010966006113524581
MGI:1860078312222125322
WBGene00010958000000120200
S000005591244442326242
WBGene00009992222222222232

GO:0005509 calcium ion binding

No significant difference from population mean. See means plot

GO:0005515 protein binding


GO:0005515 Significant 11 of 2547 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:3040955121111221111
MGI:104878111111221111
MGI:104982111111221111
MGI:107576111111221111
MGI:1913653111111221111
MGI:2661175111111221111
S000003651111111221111
S000005583111111221111
WBGene00001047111111221111
MGI:1097667121111222111
MGI:96438122121221111

GO:0005554 molecular_function unknown


GO:0005554 Significant 11 of 3156 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
S000006101111000011121
MGI:1859638101001001121
MGI:107194111111111122
MGI:1914227111111111122
MGI:2685456101000000111
MGI:2148169111111000111
S000000673000000000011
S000004822000000000011
S000001731000010000011
S000004209100110111132
S000004191100110000011

GO:0008092 cytoskeletal protein binding

No significant difference from population mean. See means plot

GO:0008135 translation factor activity, nucleic acid binding


GO:0008135 Significant 11 of 78 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:1916219111111322122
WBGene00018846111111341131
MGI:1913906222112352112
S000000003222222552132
MGI:1929520111111311131
WBGene00008920111211313111
MGI:1051251111111092322
S00000518811111210103333
WBGene00014120112111131111
S0000025791111112142211
MGI:1921398111111212111

GO:0008233 peptidase activity

No significant difference from population mean. See means plot

GO:0008289 lipid binding

No significant difference from population mean. See means plot

GO:0016209 antioxidant activity

No significant difference from population mean. See means plot

GO:0016301 kinase activity


GO:0016301 Significant 11 of 115 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
S000001664131111112111
WBGene00008230232212222222
S000005874231211111122
S000003472131211111111
WBGene00009335143111111111
MGI:1917173121111111112
WBGene00019008222211012111
S000004818232211221112
WBGene00012258131111311212
WBGene00019428145111112211
S000002516123111111111

GO:0016740 transferase activity


GO:0016740 Significant 11 of 1307 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:1916330121211111111
S000006391121211111111
MGI:2442119121111212111
S000006093121111112111
MGI:2145517121111211111
S000001710121111211111
WBGene00005020121111211111
WBGene00021002121111211111
WBGene00015693222212112111
S000001502121112111111
MGI:1098211121111111111

GO:0016787 hydrolase activity

No significant difference from population mean. See means plot

GO:0030188 chaperone regulator activity

No significant difference from population mean. See means plot

GO:0030234 enzyme regulator activity

No significant difference from population mean. See means plot

GO:0030246 carbohydrate binding


GO:0030246 Significant 11 of 326 total genes, contributing to ngenes deviation
Querydmeldsimdsecdyakderedanadperdpsedwildmojdvirdgri
MGI:97478110110001000
WBGene00012025110110000001
WBGene00007768111110000100
WBGene00009854111110000001
WBGene00017772111111000000
MGI:1891713111110001110
WBGene00011853010110110001
MGI:107540111111001110
WBGene00008891111111010111
WBGene00002267121111111111
WBGene00012103121111111111

GO:0030528 transcription regulator activity

No significant difference from population mean. See means plot

GO:0045182 translation regulator activity

No significant difference from population mean. See means plot

GO:0045735 nutrient reservoir activity

No significant difference from population mean. See means plot

Developed at the Genome Informatics Lab of Indiana University Biology Department