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Adcy4 Gene Detail
 Symbol
Name
ID
Adcy4
adenylate cyclase 4
MGI:99674


Nomenclature History
Genetic Map
Chromosome 14
cytoband D3
 
Mapping data( 1)
Sequence Map
Chr14:56387929-56402856 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: adenylate cyclase
TreeFam: TF313845
Sequences
Representative Sequences Length Strain/Species Flank
genomic 104110 NCBI Gene Model | MGI Sequence Detail 14928 C57BL/6J ± Kb
transcript NM_080435 RefSeq | MGI Sequence Detail 3414 FVB/N
polypeptide Q91WF3 UniProt | EBI | MGI Sequence Detail 1077 Not Applicable
For the selected sequences
All sequences(20)
Phenotypes All phenotypic alleles(1) : Targeted, other(1)
Mice homozygous for disruptions of this gene display a normal phenotype.
Polymorphisms SNPs within 2kb(68 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
Process activation of adenylate cyclase activity, cAMP biosynthetic process...
Component dendrite, integral to membrane...
Function adenylate cyclase activity, lyase activity...
All GO classifications(16)
Expression Literature Summary: (7 records)
Data Summary: Assays (6)    Results (279)    Tissues (183)    Images (26)
Theiler Stages: 22,23,28
  Assay Type Assays   Results
      RT-PCR 2   84
      In situ reporter (knock in) 1   40
      RNA in situ 3   155
cDNA source data(16)
External Resources: Allen Brain Atlas  GEO 
Pathways
cyclic AMP biosynthesis
Other database
links
EC 4.6.1.1
Ensembl Gene Model ENSMUSG00000022220
DoTS DT.101273065, DT.522114, DT.99856045
UniGene 287010
DFCI TC1585404, TC1722101
NIA Mouse Gene Index U035590
Entrez Gene 104110
Protein
domains
InterPro ID Description
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
IPR009398 Adenylate cyclase-like
Graphical View of Protein Domain Structure
Molecular
reagents
All nucleic(22) cDNA(18) Primer pair(2) Other(2)
References
(Earliest) J:46601 Gao BN et al., "Cloning and expression of a widely distributed (type IV) adenylyl cyclase." Proc Natl Acad Sci U S A 1991 Nov 15;88(22):10178-82
(Latest) J:122415 Michalski N et al., "Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning." J Neurosci 2007 Jun 13;27(24):6478-88
All references(12)
Other
accession IDs
MGD-MRK-16459

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/06/2009
MGI_4.13
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The Jackson Laboratory