Search     All Search Tools Genes Genes & Markers Query Batch Query Maps & Mapping Data Mouse Genome Browser Mouse Linkage Map with Orthologs Cytogenetic Maps Physical Maps Mapping Data Query RI Strain Distribution Patterns RC Strain Distribution Patterns DNA Mapping Panel Data Sets More Phenotypes Phenotypes, Alleles & Diseases Query Mammalian Phenotype (MP) Browser Human Disease (OMIM) Browser More Expression Gene Expression Literature Query Gene Expression Data Query Gene Expression Data Expanded Query Mouse Anatomical Dictionary Browser EMAGE Anatomical Section Browser cDNA Clone Query More Function GO Browser Genes & Markers Query Batch Query More Pathways Strains / SNPs SNP Query RFLP/PCR Polymorphism Query Summary of SNP Data in MGI Inbred Strain Characteristics Genealogy Chart of Inbred Strains More Orthology Orthology Query Protein Superfamily (PIRSF) Browser Mouse Linkage Map with Orthologs Mouse-Human Orthology Map Mouse-Rat Orthology Map More Tumors Sequences Sequence Query Accession IDs Query MouseBLAST Protein Superfamily (PIRSF) Browser Mouse Genome Browser Batch Query Probes & Clones Molecular Probes and Clones Query cDNA Clones Query References Reference Query Gene Expression Literature Query Vocabularies GO Browser Human Disease (OMIM) Browser Mammalian Phenotype (MP) Browser Protein Superfamily (PIRSF) Browser Mouse Anatomical Dictionary Adult Mouse Anatomy Browser Accession IDs Query Batch Query MouseBLAST Mouse Genome Browser  Download     All MGI Reports Batch Query Genes & Markers Sequence Data Mammalian Orthology Gene Ontology Data Strains & Polymorphisms Gene Expression Phenotypic Data Nomenclature References Clone Collections  More Resources       More Resources Index Research Community E-mail Lists Online Books Biology of the Laboratory Mouse edited by Earl L. Green Mouse Genetics by Lee Silver The Anatomy of the Laboratory Mouse by Margaret J. Cook The Coat Colors of Mice by Willys K. Silvers Origins of Inbred Mice edited by Herbert C. Morse III Nomenclature Home Page MGI Glossary Prototype Tools Gene Expression Notebook (GEN) Mouse Phenome Database (MPD) Deltagen and Lexicon Knockout Mice International Knockout Mouse Consortium (IKMC) Knockout Mouse Project (KOMP, USA) European Conditional Mouse Mutagenesis (EUCOMM, Europe) North American Conditional Mouse Mutagenesis (NorCOMM, Canada) Texas Institute for Genomic Medicine (TIGM, USA) Trans-NIH Mouse Initiatives Contributed Data Sets Community Links Mouse Resources & Model Organism Links Phenotypes & Mutants Community Resources Mouse Facts Software Developer Tools Creating Web Links to MGI MGI Web Service Direct SQL Account Database Schema Browser All MGI Reports More Submit Data     Find Mice (IMSR)      Contact Us

Syt1 Gene Detail  Symbol Name ID Syt1 synaptotagmin I MGI:99667 Nomenclature History Synonyms G630098F17Rik Genetic Map Chromosome 10 58.0 cM Detailed Genetic Map ± 1 cM   Mapping data( 5) Sequence Map Chr10:107934706-108448038 bp, - strand (From VEGA annotation of NCBI Build 37) VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; dog, domestic; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Syt1 ± 2 cM) Protein SuperFamily: B/K protein/synaptotagmin TreeFam: TF315600 Sequences Representative Sequences Length Strain/Species Flank genomic OTTMUSG00000016266 VEGA Gene Model | MGI Sequence Detail 513333 C57BL/6J ± Kb transcript NM_009306 RefSeq | MGI Sequence Detail 3789 - polypeptide P46096 UniProt | EBI | MGI Sequence Detail 421 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(29) Phenotypes All phenotypic alleles(6) : Targeted, knock-out(1) Targeted, other(5) Polymorphisms RFLP(2) SNPs within 2kb(2425 from dbSNP Build 128)   Gene Ontology (GO) classifications Process neurotransmitter secretion, transport... Component cell junction, cytoplasm... Function calcium ion binding, calcium-dependent phospholipid binding... All GO classifications(22) Expression Literature Summary: (17 records) Data Summary: Assays (10)    Results (183)    Tissues (118)    Images (19) Theiler Stages: 21,22,23,24,25,26,28   Assay Type Assays   Results       Western blot 6   53       RT-PCR 1   6       RNA in situ 3   124 cDNA source data(170) External Resources: Allen Brain Atlas  GENSAT  GEO  Other database links Ensembl Gene Model ENSMUSG00000035864 DoTS DT.101335131, DT.101390352, DT.482188 UniGene 289702 DFCI TC1576414, TC1598701, TC1602015 NIA Mouse Gene Index U032208 Entrez Gene 20979 VEGA Gene Model OTTMUSG00000016266 Gene Traps IST10136E5BBF1, IST10136E5HMF1, IST11479F11BBF1, IST11707A11HMF1, IST12158H10BBF1    (All 10...) Protein domains InterPro ID Description IPR000008 C2 calcium-dependent membrane targeting IPR001565 Synaptotagmin IPR015428 Synaptotagmin 1,2 Graphical View of Protein Domain Structure Molecular reagents All nucleic(178) cDNA(176) Primer pair(2) Antibodies(5) References (Earliest) J:18436 Mayanil CS et al., "Synaptic vesicle and synaptic membrane glycoproteins during pre- and postnatal development of mouse cerebral cortex, cerebellum and spinal cord." Dev Neurosci 1993;15(2):133-45 (Latest) J:136185 Hu ZT et al., "Synaptotagmin IV regulates dense core vesicle (DCV) release in LbetaT2 cells." Biochem Biophys Res Commun 2008 Jul 11;371(4):781-6 All references(57) Other accession IDs MGD-MRK-16452, MGI:2143817