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Vtn Gene Detail
 Symbol
Name
ID
Vtn
vitronectin
MGI:98940


Nomenclature History
Synonyms Vn
Genetic Map
Chromosome 11
45.09 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr11:78312593-78315826 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; pig, domestic; rabbit, European; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Vtn ± 2 cM)
Protein SuperFamily: vitronectin
TreeFam: TF332780
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000000143 VEGA Gene Model | MGI Sequence Detail 3234 C57BL/6J ± Kb
transcript NM_011707 RefSeq | MGI Sequence Detail 1586 BALB/c
polypeptide P29788 UniProt | EBI | MGI Sequence Detail 478 Not Applicable
For the selected sequences
All sequences(26)
Phenotypes All phenotypic alleles(1) : Targeted, knock-out(1)
Homozygotes and heterozygotes for a targeted null mutation appear to develop, mature, and reproduce normally.
Polymorphisms SNPs within 2kb(15 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
Process cell adhesion, cell-matrix adhesion...
Component extracellular region, proteinaceous extracellular matrix...
Function extracellular matrix binding, heparin binding...
All GO classifications(9)
Expression Literature Summary: (8 records)
Data Summary: Assays (4)    Results (185)    Tissues (145)    Images (52)
Theiler Stages: 17,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 2   25
      RNA in situ 2   160
cDNA source data(420)
External Resources: Allen Brain Atlas  GEO 
Other database
links
Ensembl Gene Model ENSMUSG00000017344
DoTS DT.55107283, DT.94137733
UniGene 3667
DFCI TC1573543
NIA Mouse Gene Index U013021
Entrez Gene 22370
VEGA Gene Model OTTMUSG00000000143
Protein
domains
InterPro ID Description
IPR000585 Hemopexin
IPR001212 Somatomedin B
Graphical View of Protein Domain Structure
Molecular
reagents
All nucleic(432) Genomic(8) cDNA(421) Primer pair(3)
References
(Earliest) J:23999 Kolb WP et al., "The membrane attack mechanism of complement. Isolation and subunit composition of the C5b-9 complex." J Exp Med 1975 Apr 1;141(4):724-35
(Latest) J:139122 Manabe R et al., "Transcriptome-based systematic identification of extracellular matrix proteins." Proc Natl Acad Sci U S A 2008 Sep 2;105(35):12849-54
All references(37)
Other
accession IDs
MGD-MRK-15418, MGI:2144094

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/06/2009
MGI_4.13
Web browser compatibility
The Jackson Laboratory