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Stat5b Gene Detail  Symbol Name ID Stat5b signal transducer and activator of transcription 5B MGI:103035 Nomenclature History Genetic Map Chromosome 11 60.5 cM Detailed Genetic Map ± 1 cM   Mapping data( 7) Sequence Map Chr11:100642045-100712038 bp, - strand (From VEGA annotation of NCBI Build 37) VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Stat5b ± 2 cM) Protein SuperFamily: signal transducer and transcription activator STAT5A TreeFam: TF318648 Sequences Representative Sequences Length Strain/Species Flank genomic OTTMUSG00000002127 VEGA Gene Model | MGI Sequence Detail 69994 C57BL/6J ± Kb transcript NM_011489 RefSeq | MGI Sequence Detail 5255 C57BL/6 polypeptide P42232 UniProt | EBI | MGI Sequence Detail 786 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(35) Phenotypes All phenotypic alleles(5) : Targeted, knock-out(4) Targeted, other(1) Mice homozygous for disruptions in this are reduced in size and mammary glands secrete reduced levels of some milk proteins during lactation. Polymorphisms RFLP(1) SNPs within 2kb(265 from dbSNP Build 128)   SNPs within 2kb including multiple locations(273) Gene Ontology (GO) classifications Process 2-oxoglutarate metabolic process, allantoin metabolic process... Component cytoplasm, nucleus... Function calcium ion binding, DNA binding... All GO classifications(56) Expression Literature Summary: (9 records) Data Summary: Assays (4)    Results (93)    Tissues (84)    Images (4) Theiler Stages: 2,3,4,5,17,21,23,28   Assay Type Assays   Results       RT-PCR 2   61       RNA in situ 2   32 cDNA source data(85) External Resources: Allen Brain Atlas  GEO  Other database links Ensembl Gene Model ENSMUSG00000020919 DoTS DT.101402191, DT.492044, DT.94230572 UniGene 34064 NIA Mouse Gene Index U033437 Entrez Gene 20851 VEGA Gene Model OTTMUSG00000002127 Gene Traps IST12334F7HMF1 Protein domains InterPro ID Description IPR000980 SH2 motif IPR001217 STAT transcription factor, core IPR011992 EF-Hand type IPR012345 STAT transcription factor, DNA-binding, subdomain IPR013799 STAT transcription factor, protein interaction IPR013800 STAT transcription factor, all-alpha IPR013801 STAT transcription factor, DNA-binding Graphical View of Protein Domain Structure Molecular reagents All nucleic(95) Genomic(7) cDNA(86) Primer pair(2) References (Earliest) J:24359 Mui AL et al., "Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs." EMBO J 1995 Mar 15;14(6):1166-75 (Latest) J:142128 Kerenyi MA et al., "Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1." Blood 2008 Nov 1;112(9):3878-88 All references(125) Other accession IDs MGD-MRK-23873