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Pcsk6 Gene Detail  Symbol Name ID Pcsk6 proprotein convertase subtilisin/kexin type 6 MGI:102897 Nomenclature History Synonyms PACE4, SPC4 Genetic Map Chromosome 7 28.5 cM Detailed Genetic Map ± 1 cM   Mapping data( 5) Sequence Map Chr7:73007099-73195220 bp, + strand (From Ensembl annotation of NCBI Build 37) Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; chimpanzee; dog, domestic; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Pcsk6 ± 2 cM) Protein SuperFamily: proprotein convertase, subtilisin/kexin types TreeFam: TF314277 Sequences Representative Sequences Length Strain/Species Flank genomic ENSMUSG00000030513 Ensembl Gene Model | MGI Sequence Detail 188122 C57BL/6J ± Kb transcript BC037450 GenBank | EMBL | DDBJ | MGI Sequence Detail 3826 CZECHII polypeptide Q62030 UniProt | EBI | MGI Sequence Detail 932 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(37) Phenotypes All phenotypic alleles(1) : Targeted, knock-out(1) Polymorphisms RFLP(1) SNPs within 2kb(1473 from dbSNP Build 128)   Gene Ontology (GO) classifications Process determination of left/right symmetry, zygotic determination of anterior/posterior axis, embryo... All GO classifications(3) Expression Literature Summary: (14 records) Data Summary: Assays (4)    Results (20)    Tissues (19)    Images (3) Theiler Stages: 16,17,21,22,23   Assay Type Assays   Results       RT-PCR 1   2       RNA in situ 3   18 cDNA source data(19) External Resources: Allen Brain Atlas  GEO  Other database links Ensembl Gene Model ENSMUSG00000030513 DoTS DT.101178696, DT.101399918, DT.489888 DFCI TC1598112, TC1601297, TC1603517 NIA Mouse Gene Index U042815 Entrez Gene 18553 Gene Traps 3SD124B09, IST10224C4HMF1, IST10371F12BBF1, IST10815A2HMF1, IST10944H3BBF1    (All 51...) Protein domains InterPro ID Description IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin IPR002884 Proprotein convertase, P IPR006210 EGF IPR006212 Furin-like repeat IPR007087 Zinc finger, C2H2-type IPR010909 PLAC IPR015500 Peptidase S8, subtilisin-related Molecular reagents All nucleic(23) Genomic(1) cDNA(20) Primer pair(2) References (Earliest) J:52522 Steiner DF et al., "The new enzymology of precursor processing endoproteases." J Biol Chem 1992 Nov 25;267(33):23435-8 (Latest) J:140467 Scamuffa N et al., "Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7." Gut 2008 Nov;57(11):1573-82 All references(32) Other accession IDs MGD-MRK-23731, MGI:2142365