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Klkb1 Gene Detail
 Symbol
Name
ID
Klkb1
kallikrein B, plasma 1
MGI:102849


Nomenclature History
Synonyms Kal-3, Kal3, Klk3
Genetic Map
Chromosome 8
26.0 cM, cytoband B1-B3
Detailed Genetic Map ± 1 cM
 
Mapping data( 9)

Sequence Map
Chr8:46355025-46393820 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Klkb1 ± 2 cM)
Protein SuperFamily: plasma kallikrein/coagulation factor XI
TreeFam: TF343687
Sequences
Representative Sequences Length Strain/Species Flank
genomic 16621 NCBI Gene Model | MGI Sequence Detail 38796 C57BL/6J ± Kb
transcript NM_008455 RefSeq | MGI Sequence Detail 2753 BALB/c
polypeptide P26262 UniProt | EBI | MGI Sequence Detail 638 Not Applicable
For the selected sequences
All sequences(10)
Polymorphisms PCR(2) SNPs within 2kb(588 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
Process blood coagulation, fibrinolysis...
Component extracellular region
Function hydrolase activity, peptidase activity...
All GO classifications(11)
Expression cDNA source data(4)
External Resources: Allen Brain Atlas  GEO 
Other database
links
EC 3.4.21.34
Ensembl Gene Model ENSMUSG00000031640
DoTS DT.91411616
DFCI TC1583928
Entrez Gene 16621
Protein
domains
InterPro ID Description
IPR000177 Apple
IPR001254 Peptidase S1 and S6, chymotrypsin/Hap
IPR001314 Peptidase S1A, chymotrypsin
IPR003014 N/apple PAN
IPR003609 Apple-like
Graphical View of Protein Domain Structure
Molecular
reagents
All nucleic(9) Genomic(2) cDNA(5) Primer pair(2)
References
(Earliest) J:10905 Seidah NG et al., "Mouse plasma kallikrein: cDNA structure, enzyme characterization, and comparison of protein and mRNA levels among species." DNA Cell Biol 1990 Dec;9(10):737-48
(Latest) J:125335 Nishihara E et al., "Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJ x C3H/HeJ intercrosses." Mamm Genome 2007 Aug;18(8):573-83
All references(7)
Other
accession IDs
MGD-MRK-11549, MGD-MRK-11550, MGD-MRK-23682

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/08/2009
MGI_4.13
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