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Six2 Gene Detail
 Symbol
Name
ID
Six2
sine oculis-related homeobox 2 homolog (Drosophila)
MGI:102778


Nomenclature History
Genetic Map
Chromosome 17
45.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 3)

Sequence Map
Chr17:86083622-86087594 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Six2 ± 2 cM)
TreeFam: TF315545
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000024134 Ensembl Gene Model | MGI Sequence Detail 3973 C57BL/6J ± Kb
transcript NM_011380 RefSeq | MGI Sequence Detail 2095 BALB/c
polypeptide Q62232 UniProt | EBI | MGI Sequence Detail 296 Not Applicable
For the selected sequences
All sequences(12)
Phenotypes All phenotypic alleles(1) : Targeted, knock-out(1)
Polymorphisms RFLP(1) SNPs within 2kb(4 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
Process embryonic skeletal system morphogenesis, metanephros development...
Component nucleus
Function DNA binding, protein binding...
All GO classifications(15)
Expression Literature Summary: (29 records)
Data Summary: Assays (8)    Results (95)    Tissues (80)    Images (41)
Theiler Stages: 13,15,17,18,19,20,21,22,23,24,28
  Assay Type Assays   Results
      RNA in situ 7   94
      Northern blot 1   1
cDNA source data(10)
External Resources: Allen Brain Atlas  GEO 
Other database
links
Ensembl Gene Model ENSMUSG00000024134
DoTS DT.55164665, DT.87040511
UniGene 5039
DFCI TC1590264
Entrez Gene 20472
Protein
domains
InterPro ID Description
IPR000047 Helix-turn-helix motif, lambda-like repressor
IPR001356 Homeobox
IPR012287 Homeodomain-related
Graphical View of Protein Domain Structure
Molecular
reagents
All nucleic(13) cDNA(10) Other(3)
References
(Earliest) J:23775 Oliver G et al., "Homeobox genes and connective tissue patterning." Development 1995 Mar;121(3):693-705
(Latest) J:137524 Mugford JW et al., "Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo." Dev Biol 2008 Jul 15;319(2):396-405
All references(37)
Other
accession IDs
MGD-MRK-19686

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/08/2009
MGI_4.13
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The Jackson Laboratory