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Pou4f2 Gene Detail
 Symbol
Name
ID
Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524


Nomenclature History
Synonyms Brn-3.2, Brn-3b, Brn3b, mBrn3-3R, Pou4f-rs1
Genetic Map
Chromosome 8
cytoband F1-F5
 
Mapping data( 3)
Sequence Map
Chr8:80956908-80960551 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
Protein SuperFamily: POU domain class 4 transcription factor, Brn3 type
TreeFam: TF316413
Sequences
Representative Sequences Length Strain/Species Flank
genomic 18997 NCBI Gene Model | MGI Sequence Detail 3644 C57BL/6J ± Kb
transcript NM_138944 RefSeq | MGI Sequence Detail 3212 C57BL/6
polypeptide Q63934 UniProt | EBI | MGI Sequence Detail 411 Not Applicable
For the selected sequences
All sequences(18)
Phenotypes All phenotypic alleles(6) : Targeted, knock-out(2) Targeted, other(4)
Polymorphisms RFLP(1) SNPs within 2kb(5 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
Process axon extension involved in development, axon guidance...
Component nucleus
Function chromatin binding, DNA binding...
All GO classifications(25)
Expression Literature Summary: (78 records)
Data Summary: Assays (17)    Results (88)    Tissues (62)    Images (22)
Theiler Stages: 15,16,17,18,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 5   22
      RNA in situ 3   9
      Immunohistochemistry 3   13
      Northern blot 2   2
      RNase protection 4   42
cDNA source data(13)
External Resources: Allen Brain Atlas  GEO 
Other database
links
Ensembl Gene Model ENSMUSG00000031688
DoTS DT.91381361
UniGene 234261
DFCI TC1585350
NIA Mouse Gene Index U029986
Entrez Gene 18997
Protein
domains
InterPro ID Description
IPR000327 POU-specific
IPR001356 Homeobox
IPR012287 Homeodomain-related
IPR013847 POU
IPR015584 POU domain class 4 related
Graphical View of Protein Domain Structure
Molecular
reagents
All nucleic(25) Genomic(6) cDNA(13) Primer pair(5) Other(1) Antibodies(2)
References
(Earliest) J:9856 He X et al., "Expression of a large family of POU-domain regulatory genes in mammalian brain development [published erratum appears in Nature 1989 Aug 24;340(6235):662]" Nature 1989 Jul 6;340(6228):35-41
(Latest) J:141248 Mao CA et al., "Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5." Development 2008 Oct;135(20):3379-88
All references(91)
Other
accession IDs
MGD-MRK-1631, MGD-MRK-19368, MGD-MRK-19462, MGI:102576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/08/2009
MGI_4.13
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