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Pou4f3 Gene Detail  Symbol Name ID Pou4f3 POU domain, class 4, transcription factor 3 MGI:102523 Nomenclature History Synonyms Brn-3.1, Brn3.1, Brn3c Genetic Map Chromosome 18 24.0 cM, cytoband B3-E1 Detailed Genetic Map ± 1 cM   Mapping data( 3) Sequence Map Chr18:42554297-42555664 bp, + strand (From NCBI annotation of NCBI Build 37) Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; chimpanzee; dog, domestic; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Pou4f3 ± 2 cM) Protein SuperFamily: POU domain class 4 transcription factor, Brn3 type TreeFam: TF316413 Sequences Representative Sequences Length Strain/Species Flank genomic 18998 NCBI Gene Model | MGI Sequence Detail 1368 C57BL/6J ± Kb transcript NM_138945 RefSeq | MGI Sequence Detail 1017 CD-1 polypeptide Q63955 UniProt | EBI | MGI Sequence Detail 338 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(9) Phenotypes All phenotypic alleles(4) : Targeted, knock-out(2) Targeted, other(1) Spontaneous(1) Phenotype Images (5)   Polymorphisms SNPs within 2kb(3 from dbSNP Build 128)   Gene Ontology (GO) classifications Process auditory receptor cell differentiation, axon extension involved in development... Component nucleus, transcription factor complex... Function DNA binding, sequence-specific DNA binding... All GO classifications(23) Expression Literature Summary: (21 records) Data Summary: Assays (8)    Results (82)    Tissues (55)    Images (36) Theiler Stages: 17,18,19,20,21,22,23,24,25,26,28   Assay Type Assays   Results       RT-PCR 1   7       RNA in situ 2   34       Immunohistochemistry 3   39       Northern blot 2   2 cDNA source data(5) External Resources: Allen Brain Atlas  GENSAT  GEO  Other database links Ensembl Gene Model ENSMUSG00000024497 DoTS DT.101315185 UniGene 221181 Entrez Gene 18998 Protein domains InterPro ID Description IPR000327 POU-specific IPR001356 Homeobox IPR012287 Homeodomain-related IPR013847 POU IPR015584 POU domain class 4 related Graphical View of Protein Domain Structure Molecular reagents All nucleic(14) Genomic(7) cDNA(6) Primer pair(1) Antibodies(1) References (Earliest) J:16381 Theil T et al., "Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a." Nucleic Acids Res 1993 Dec 25;21(25):5921-9 (Latest) J:119779 Hertzano R et al., "Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system." Eur J Neurosci 2007 Feb;25(4):999-1005 All references(32) Other accession IDs MGD-MRK-1632, MGD-MRK-19367, MGI:1342649