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Wnt11 Gene Detail  Symbol Name ID Wnt11 wingless-related MMTV integration site 11 MGI:101948 Nomenclature History Genetic Map Chromosome 7 48.0 cM Detailed Genetic Map ± 1 cM   Mapping data( 14) Sequence Map Chr7:105987355-106002258 bp, + strand (From NCBI annotation of NCBI Build 37) Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; chimpanzee; dog, domestic; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Wnt11 ± 2 cM) Protein SuperFamily: int-1 transforming protein TreeFam: TF105310 Sequences Representative Sequences Length Strain/Species Flank genomic 22411 NCBI Gene Model | MGI Sequence Detail 14904 C57BL/6J ± Kb transcript NM_009519 RefSeq | MGI Sequence Detail 1821 - polypeptide P48615 UniProt | EBI | MGI Sequence Detail 354 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(18) Phenotypes All phenotypic alleles(1) : Targeted, knock-out(1) Homozygous mutation of this gene results in extensive embryonic lethality and mutants surviving to birth die within the first 2 days of life. The kidneys are small and exhibit delayed development. Polymorphisms RFLP(1) SNPs within 2kb(110 from dbSNP Build 128)   Gene Ontology (GO) classifications Process cell-cell signaling, multicellular organismal development... Component extracellular region, proteinaceous extracellular matrix... Function receptor binding, signal transducer activity... All GO classifications(12) Expression Literature Summary: (66 records) Data Summary: Assays (24)    Results (286)    Tissues (222)    Images (72) Theiler Stages: 1,2,3,4,5,6,8,9,10,11,12,13,14,15,17,18,19,20,21,22,23,24,26,28   Assay Type Assays   Results       RT-PCR 11   83       RNA in situ 11   195       Immunohistochemistry 1   6       RNase protection 1   2 cDNA source data(16) External Resources: Allen Brain Atlas  GEO  Other database links Ensembl Gene Model ENSMUSG00000015957 DoTS DT.40147241, DT.94230101 UniGene 22182 DFCI TC1587635, TC1597606 NIA Mouse Gene Index U008431 Entrez Gene 22411 Protein domains InterPro ID Description IPR005816 Secreted growth factor Wnt protein IPR005817 Wnt superfamily Graphical View of Protein Domain Structure Molecular reagents All nucleic(30) cDNA(18) Primer pair(9) Other(3) Antibodies(1) References (Earliest) J:21464 Adamson MC et al., "Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a." Genomics 1994 Nov 1;24(1):9-13 (Latest) J:139251 Lin C et al., "Tissue-specific requirements of beta-catenin in external genitalia development." Development 2008 Aug;135(16):2815-25 All references(81) Other accession IDs MGD-MRK-18782