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E2f1 Gene Detail  Symbol Name ID E2f1 E2F transcription factor 1 MGI:101941 Nomenclature History Synonyms E2F-1 Genetic Map Chromosome 2 84.0 cM Detailed Genetic Map ± 1 cM   Mapping data( 7) Sequence Map Chr2:154385143-154395628 bp, - strand (From VEGA annotation of NCBI Build 37) VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; dog, domestic; rat    (Mammalian Orthology) Comparative Map (Mouse/Human E2f1 ± 2 cM) Protein SuperFamily: transcription factor E2F TreeFam: TF105566 Sequences Representative Sequences Length Strain/Species Flank genomic OTTMUSG00000015917 VEGA Gene Model | MGI Sequence Detail 10486 C57BL/6J ± Kb transcript NM_007891 RefSeq | MGI Sequence Detail 2460 - polypeptide Q61501 UniProt | EBI | MGI Sequence Detail 430 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(29) Phenotypes All phenotypic alleles(2) : Targeted, knock-out(2) Associated Human Diseases (2)   Alleles Annotated to Human Diseases (1)   Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(33 from dbSNP Build 128)   Gene Ontology (GO) classifications Process apoptosis, cell cycle... Component cytoplasm, nucleus... Function DNA binding, protein binding... All GO classifications(18) Expression Literature Summary: (22 records) Data Summary: Assays (13)    Results (113)    Tissues (77)    Images (9) Theiler Stages: 2,3,4,5,15,16,17,19,20,21,22,24,25,26,28   Assay Type Assays   Results       Western blot 7   44       RT-PCR 2   17       RNA in situ 4   52 cDNA source data(40) External Resources: Allen Brain Atlas  GEO  Other database links Ensembl Gene Model ENSMUSG00000027490 DoTS DT.487843, DT.55242765, DT.94214859 UniGene 18036 DFCI TC1580685, TC1589446, TC1672614 NIA Mouse Gene Index U023524 Entrez Gene 13555 VEGA Gene Model OTTMUSG00000015917 Gene Traps CMHD-GT_294C7-3, OST190536, OST300238, OST376235 Protein domains InterPro ID Description IPR003316 Transcription factor E2F/dimerisation partner (TDP) IPR011991 Winged helix repressor DNA-binding IPR015633 E2F Family IPR015634 Transcription Factor E2F1 Graphical View of Protein Domain Structure Molecular reagents All nucleic(53) Genomic(7) cDNA(41) Primer pair(3) Other(2) Antibodies(3) References (Earliest) J:16207 Carlsten H et al., "Histocompatibility complex gene products and exposure to oestrogen: two independent disease accelerating factors in murine lupus." Scand J Immunol 1993 Oct;38(4):341-7 (Latest) J:142320 Hsieh MC et al., "Regulation of the PDK4 isozyme by the Rb-E2F1 complex." J Biol Chem 2008 Oct 10;283(41):27410-7 All references(156) Other accession IDs MGD-MRK-18775