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Tfdp1 Gene Detail  Symbol Name ID Tfdp1 transcription factor Dp 1 MGI:101934 Nomenclature History Synonyms Dp1, Drtf1 Genetic Map Chromosome 8 cytoband A1-A3   Mapping data( 5) Sequence Map Chr8:13339674-13377702 bp, + strand (From NCBI annotation of NCBI Build 37) Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; dog, domestic    (Mammalian Orthology) Protein SuperFamily: transcription factor DP TreeFam: TF314396 Sequences Representative Sequences Length Strain/Species Flank genomic 21781 NCBI Gene Model | MGI Sequence Detail 38029 C57BL/6J ± Kb transcript NM_009361 RefSeq | MGI Sequence Detail 1700 - polypeptide Q08639 UniProt | EBI | MGI Sequence Detail 410 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(29) Phenotypes All phenotypic alleles(1) : Targeted, knock-out(1) Homozygotes for a targeted null mutation exhibit reduced expansion of the ectoplacental cone and chorion, small yolk sacs, and impaired endoreduplication in trophoblast giant cells. Mutants die by embryonic day 12.5. Polymorphisms SNPs within 2kb(213 from dbSNP Build 128)   Gene Ontology (GO) classifications Process apoptosis, cell cycle... Component nucleus, transcription factor complex... Function DNA binding, protein binding... All GO classifications(16) Expression Literature Summary: (12 records) Data Summary: Assays (8)    Results (79)    Tissues (62)    Images (14) Theiler Stages: 2,3,4,5,17,18,21,23,24,26,28   Assay Type Assays   Results       Western blot 3   20       RT-PCR 1   15       RNA in situ 4   44 cDNA source data(10) External Resources: Allen Brain Atlas  GEO  Other database links Ensembl Gene Model ENSMUSG00000038482 DoTS DT.101239430, DT.101737934, DT.110631907, DT.94156122, DT.94156134, DT.99860040 DFCI TC1574248, TC1605725 NIA Mouse Gene Index U009104, U136210 Entrez Gene 21781 Gene Traps 5SE130E08, AD0723, AM0518, CSE052, CSE124    (All 22...) Protein domains InterPro ID Description IPR003316 Transcription factor E2F/dimerisation partner (TDP) IPR011991 Winged helix repressor DNA-binding IPR014889 Transcription factor DP, C-terminal IPR015648 Transcription factor DP IPR016556 Transcription factor DP, subgroup Graphical View of Protein Domain Structure Molecular reagents All nucleic(20) Genomic(4) cDNA(13) Primer pair(1) Other(2) Antibodies(2) References (Earliest) J:17080 Girling R et al., "A new component of the transcription factor DRTF1/E2F [published erratum appears in Nature 1993 Sep 30;365(6445):468]" Nature 1993 Mar 4;362(6415):83-7 (Latest) J:121306 Abba MC et al., "Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34." Cancer Res 2007 May 1;67(9):4104-12 All references(24) Other accession IDs MGD-MRK-18766