Search     All Search Tools Genes Genes & Markers Query Batch Query Maps & Mapping Data Mouse Genome Browser Mouse Linkage Map with Orthologs Cytogenetic Maps Physical Maps Mapping Data Query RI Strain Distribution Patterns RC Strain Distribution Patterns DNA Mapping Panel Data Sets More Phenotypes Phenotypes, Alleles & Diseases Query Mammalian Phenotype (MP) Browser Human Disease (OMIM) Browser More Expression Gene Expression Literature Query Gene Expression Data Query Gene Expression Data Expanded Query Mouse Anatomical Dictionary Browser EMAGE Anatomical Section Browser cDNA Clone Query More Function GO Browser Genes & Markers Query Batch Query More Pathways Strains / SNPs SNP Query RFLP/PCR Polymorphism Query Summary of SNP Data in MGI Inbred Strain Characteristics Genealogy Chart of Inbred Strains More Orthology Orthology Query Protein Superfamily (PIRSF) Browser Mouse Linkage Map with Orthologs Mouse-Human Orthology Map Mouse-Rat Orthology Map More Tumors Sequences Sequence Query Accession IDs Query MouseBLAST Protein Superfamily (PIRSF) Browser Mouse Genome Browser Batch Query Probes & Clones Molecular Probes and Clones Query cDNA Clones Query References Reference Query Gene Expression Literature Query Vocabularies GO Browser Human Disease (OMIM) Browser Mammalian Phenotype (MP) Browser Protein Superfamily (PIRSF) Browser Mouse Anatomical Dictionary Adult Mouse Anatomy Browser Accession IDs Query Batch Query MouseBLAST Mouse Genome Browser  Download     All MGI Reports Batch Query Genes & Markers Sequence Data Mammalian Orthology Gene Ontology Data Strains & Polymorphisms Gene Expression Phenotypic Data Nomenclature References Clone Collections  More Resources       More Resources Index Research Community E-mail Lists Online Books Biology of the Laboratory Mouse edited by Earl L. Green Mouse Genetics by Lee Silver The Anatomy of the Laboratory Mouse by Margaret J. Cook The Coat Colors of Mice by Willys K. Silvers Origins of Inbred Mice edited by Herbert C. Morse III Nomenclature Home Page MGI Glossary Prototype Tools Gene Expression Notebook (GEN) Mouse Phenome Database (MPD) Deltagen and Lexicon Knockout Mice International Knockout Mouse Consortium (IKMC) Knockout Mouse Project (KOMP, USA) European Conditional Mouse Mutagenesis (EUCOMM, Europe) North American Conditional Mouse Mutagenesis (NorCOMM, Canada) Texas Institute for Genomic Medicine (TIGM, USA) Trans-NIH Mouse Initiatives Contributed Data Sets Community Links Mouse Resources & Model Organism Links Phenotypes & Mutants Community Resources Mouse Facts Software Developer Tools Creating Web Links to MGI MGI Web Service Direct SQL Account Database Schema Browser All MGI Reports More Submit Data     Find Mice (IMSR)      Contact Us

Dlx5 Gene Detail  Symbol Name ID Dlx5 distal-less homeobox 5 MGI:101926 Nomenclature History Genetic Map Chromosome 6 2.0 cM Detailed Genetic Map ± 1 cM   Mapping data( 2) Sequence Map Chr6:6827805-6832068 bp, - strand (From VEGA annotation of NCBI Build 37) VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; chimpanzee; rat    (Mammalian Orthology) Comparative Map (Mouse/Human Dlx5 ± 2 cM) TreeFam: TF350606 Sequences Representative Sequences Length Strain/Species Flank genomic OTTMUSG00000021177 VEGA Gene Model | MGI Sequence Detail 4264 C57BL/6J ± Kb transcript NM_010056 RefSeq | MGI Sequence Detail 1431 - polypeptide P70396 UniProt | EBI | MGI Sequence Detail 289 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(33) Phenotypes All phenotypic alleles(5) : Targeted, knock-out(1) Targeted, other(4) Homozygous null mutants display multiple defects in craniofacial structures, including ears, nose, mandible and calvaria, and die shortly after birth, with some exhibiting exencephaly. Associated Human Diseases (1)   Alleles Annotated to Human Diseases (2)   Polymorphisms SNPs within 2kb(55 from dbSNP Build 128)   Gene Ontology (GO) classifications Process anatomical structure formation, axonogenesis... Component cytoplasm, nucleus... Function DNA binding, protein binding... All GO classifications(17) Expression Literature Summary: (131 records) Data Summary: Assays (27)    Results (308)    Tissues (239)    Images (76) Theiler Stages: 8,9,10,11,12,13,14,15,17,18,19,20,21,22,23,24,25,26,28   Assay Type Assays   Results       RT-PCR 4   28       In situ reporter (knock in) 1   1       RNA in situ 19   256       Immunohistochemistry 2   21       Northern blot 1   2 cDNA source data(22) External Resources: Allen Brain Atlas  GENSAT  GEO  Other database links Ensembl Gene Model ENSMUSG00000029755 DoTS DT.101122016, DT.101364077, DT.485672, DT.87050939, DT.97359781 UniGene 4873 DFCI TC1584528, TC1596772 NIA Mouse Gene Index U027033 Entrez Gene 13395 VEGA Gene Model OTTMUSG00000021177 Protein domains InterPro ID Description IPR000047 Helix-turn-helix motif, lambda-like repressor IPR001356 Homeobox IPR012287 Homeodomain-related Graphical View of Protein Domain Structure Molecular reagents All nucleic(40) Genomic(2) cDNA(24) Primer pair(6) Other(8) Antibodies(1) References (Earliest) J:17176 Simeone A et al., "Cloning and characterization of two members of the vertebrate Dlx gene family." Proc Natl Acad Sci U S A 1994 Mar 15;91(6):2250-4 (Latest) J:142510 Abraira VE et al., "Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear." Development 2008 Dec;135(24):4091-9 All references(144) Other accession IDs MGD-MRK-18757, MGI:2141401