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Tbp Gene Detail  Symbol Name ID Tbp TATA box binding protein MGI:101838 Nomenclature History Synonyms Gtf2d Genetic Map Chromosome 17 8.254 cM Detailed Genetic Map ± 1 cM   Mapping data( 13) Sequence Map Chr17:15636852-15654391 bp, + strand (From VEGA annotation of NCBI Build 37) VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer Mouse Genome Browser Mammalian homology human; dog, domestic; rat; hamster, golden    (Mammalian Orthology) Comparative Map (Mouse/Human Tbp ± 2 cM) Protein SuperFamily: human transcription initiation factor IID TreeFam: TF300102 Sequences Representative Sequences Length Strain/Species Flank genomic OTTMUSG00000030550 VEGA Gene Model | MGI Sequence Detail 17540 C57BL/6J ± Kb transcript NM_013684 RefSeq | MGI Sequence Detail 1842 C57BL/6 polypeptide P29037 UniProt | EBI | MGI Sequence Detail 316 Not Applicable For the selected sequences download in FASTA format forward to MouseBLAST All sequences(28) Phenotypes All phenotypic alleles(3) : Targeted, knock-out(1) Targeted, other(2) Mice homozygous for one null allele exhibit embryonic lethality caused by hemorrhaging and clotting in the placenta and surviving embryos die prior to weaning. Mice homozygous for another null allele undergo growth arrest after hatching and apoptosis. Polymorphisms RFLP(2) SNPs within 2kb(71 from dbSNP Build 128)   Gene Ontology (GO) classifications Process regulation of transcription, DNA-dependent, transcription... Component female pronucleus, male pronucleus... Function binding, DNA binding... All GO classifications(13) Expression Literature Summary: (23 records) Data Summary: Assays (15)    Results (110)    Tissues (77)    Images (25) Theiler Stages: 1,2,3,4,5,13,17,20,21,22,23,24,26,28   Assay Type Assays   Results       RT-PCR 10   61       RNA in situ 5   49 cDNA source data(65) External Resources: Allen Brain Atlas  GENSAT  GEO  Other database links Ensembl Gene Model ENSMUSG00000014767 DoTS DT.101377423, DT.101377425, DT.91594787, DT.94142848 UniGene 244820 DFCI TC1577485, TC1608407, TC1637361 Entrez Gene 21374 VEGA Gene Model OTTMUSG00000030550 Gene Traps AH0535, IST12344E6BBF1, IST12344E6HMF1, OST452452, RRS626 Protein domains InterPro ID Description IPR000814 TATA-box binding IPR012295 Beta2-adaptin/TATA-box binding, C-terminal Graphical View of Protein Domain Structure Molecular reagents All nucleic(84) Genomic(11) cDNA(67) Primer pair(5) Other(1) References (Earliest) J:21431 Tamura T et al., "Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID)." Nucleic Acids Res 1991 Jul 25;19(14):3861-5 (Latest) J:138818 Tatarakis A et al., "Dominant and redundant functions of TFIID involved in the regulation of hepatic genes." Mol Cell 2008 Aug 22;31(4):531-43 All references(49) Other accession IDs MGD-MRK-18659, MGD-MRK-24009